Luca Signorelli started his life as a painter apprenticed to Piero della Francesca, who was to have a strong influence over him, such that, as Vasari says, it was sometimes difficult to distinguish their work. In the early 1480s he worked on the fresco decoration of the side walls of the Sistine Chapel, before coming to Florence, where he learned a great deal from the artists already living there, and also worked for Lorenzo the Magnificent. Luca Signorelli explores the painter's life, work, and influences, incorporating time spent in Florence and Rome, and works produced there. His paintings are presented in full colour, including the ceiling of the Chapel of San Brizio, and his depiction of the Apocalypse in the Orvieto chapel.