This interactive CD-ROM is designed to support national health authorities and blood transfusion services in establishing effective systems to minimize unnecessary transfusions and their associated risks of risks of transfusion reactions and transfusion-transmitted infection. It also provides comprehensive materials to assist individual clinicians in making appropriate prescribing decisions about transfusion and alternatives to transfusion. The CD-ROM includes: Aide-Mémoire for National Health Programs: The Clinical Use of Blood which provides a brief guide for policy makers on requirements for the appropriate use of blood, including a national policy and guidelines on transfusion, hospital transfusion committees, education and training, and systems for monitoring and evaluation. Recommendations: Developing a National Policy and Guidelines on the Clinical Use of Blood, a concise guide to the steps involved in developing a national policy on the clinical use of blood and the elements that should be included in national transfusion guidelines. The Clinical Use of Blood: Handbook which provides a comprehensive reference to the appropriate use of blood and blood products in general medicine, obstetrics, pediatrics, surgery and anesthesia, trauma and burns, and The Clinical Use of Blood in Medicine, Obstetrics, Pediatrics, Surgery & Anesthesia, Trauma & Burns, a module of learning material on the use of whole blood, blood products and alternatives to transfusion. It includes an extensive range of activities to promote improvements in clinical transfusion practice.