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Gene Machine: The Race to Decipher the Secrets of the Ribosome (2018)

de Venki Ramakrishnan

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1383197,751 (3.38)Cap
Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome-an enormous molecular machine made up of a million atoms-that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.… (més)
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Talks about how the structure of the ribosome was "solved". It also discusses scientific competition and awards. ( )
  Castinet | Dec 11, 2022 |
Look I don't like biology and I enjoyed this book. The author walks a fine line between modesty and self-promotion, but hey as a Nobel prize winner, I guess a little bragging is warranted. Worth the read. ( )
  Skybalon | Mar 19, 2020 |
What an interesting little book! I have to say, I never thought I'd read a book that centered so much around the ribosome, but my high school biology teacher would be proud. Ramakrishnan's life and story gripped me from the start and he did well incorporating both science and memoir into his novel.

I received an advanced copy through Netgalley in return for an honest review. ( )
  Kristymk18 | Jan 30, 2019 |
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Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome-an enormous molecular machine made up of a million atoms-that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.

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