William Burroughs arrives in 1949 to the city of Mexico accompanied by Joan, his wife, his step-daughter Julie and Billy, their infant son. Destined to become the most important contemporary experimental writer of the United States, the still young Bill just flirts with the idea of writing a novel. It ignores that two years later he would accidentally kill Joan of a shot in the head, during a stupid game of William Tell. In 1990 a very young Bef discovers by accident the work of Burroughs, countercultural writer and patriarch of the beatnik generation. Knowing that Burroughs lived in his town and walked the same streets will have to obsess over the following years. "Uncle Bill" tells the story of the cultural clash of Burroughs with Mexico, his previous setbacks before fleeing to the still provincial Federal District and the fatal accident, as well as his fleeting passage through Lecumberri prison and the relationship of love - hate that a reader can be set with the work of an author of that separate time and space, as well as the strange bond that seems to unite them. "Uncle Bill" is the most ambitious graphic novel from one of the most important writers and cartoonists in Mexico. "Bef entered one of the most dramatic episodes of the literature-the turbulent life of William S. Burroughs in Mexico to achieve a literary masterpiece. Research and murder mysteries of creativity, this graphic novel is the autobiography of Bef, the hallucinating artist who plasma in black and white all the colors of the mind.".